You're kind of saying "look over here!" but I'm not that easily distracted.
You said "Which will also become a historical artifact as new protocols are made to use little endian". It's never going to become a historical artifact in our lifetimes. As the peer poster pointed out, QUIC itself has big-endian header fields. IPv4/IPv6 both use big-endian at layer 3.
The OSI layer model is extremely relevant to the Cisco network engineers running the edges of the large FAANG companies, hyperscalers etc. that connect them to the internet.
I was wrong about QUIC, for some reason I was sure I'd read it's little-endian.
I'm just pointing out that UDP is an extremely thin wrapper over IP and the preferred way of implementing new protocols. It seems likely we'll eventually replace at least some of our protocols and deprecate old ones and I was under the impression new ones tended to be little endian.
Foolishly, QUIC is not little-endian [1]. The headers are defined to be big-endian. Though, obviously, none of UDP, TCP, or QUIC define the endianness of their payload so you can at least kill it at that layer.