> Our study identified altered signal intensity, abnormal tissue microstructure, and imbalanced neurochemicals in long COVID and COVID-19 recovered healthy controls.
So, it seems that it has long lasting effects on everybody. The main difference is how severe are that effects.
> Structural MRI studies have also identified alterations in brain morphology among COVID-RHC, including reductions in grey matter volume, thickness and global brain volume when compared with healthy controls
That is scary.
> Furthermore, long-term follow-up studies are crucial to determine whether the identified brain changes are progressive, stable or dynamic over time.
This is interesting, thou. Is it permanent, it gets worse or better? That makes a big difference and it may also justify further studies and actions.
>Importantly, cognitive impairments are not limited to those with ongoing systemic symptoms; they are also evident in COVID-19 recovered individuals (COVID-RHC) who no longer report active symptoms, compared to healthy controls without SARS-CoV-2 infection (Non-COVID-HC) (Hampshire et al., 2021)
The finding was done in 2021, it's not clear to me if it's an issue years out or it's just a manifestation of post-viral syndrome. Also today there are unlikely to be any people who haven't been infected by sars-cov2
Well, even the antibody titre isn't foolproof (some people do not react or have their immune system later wiped).
However having no antibody titre is pretty good sign you never had it.
Not sure if there's a portable cheap blood test for it yet. Should be one, like for the active disease.
> Is it permanent, it gets worse or better? That makes a big difference and it may also justify further studies and actions.
Some symptoms of long COVID do lessen over time. The problem is that anybody who doesn't take adequate preventative measures (vast majority) are constantly re-infecting themselves every 6-12 months, so their body never has a chance to recover.
Even vaccinated individuals are not safe. The only real protection is regular use of a well fitting N95 in public spaces, and making sure everyone in your household does the same.
Accountability and responsibility is necessary for any society to function. When corporations get all the profit while they externalize all the cost the result is a dystopia.
The rich should be forced to suffer the consequences of their actions, otherwise they have no incentive to respect the health or even life of the rest of citizens.
> When I started working, more than 25 years ago, we had one team meeting per week (1 hour), very few other meetings.
When I worked 25 years ago, I had the same experience. But software was way simpler than today. The scale and complexity of current software requires a level of organization and communication that was not needed with simpler needs.
Most software run on a PC with probably no internet connection. Updating the software required to send discs by mail. Everything was slower, and probably more robust. Maybe banking was closer to what we have now, but it was still slower and there were way less transactions.
In contrast, my last 3 jobs required backend services available 24/7 to serve millions of users worldwide. We had many data providers, and we provided services to dozens of big corporations. We had teams dedicated to just integrate to all the partners, wallets, data providers, etc.
Increased complexity requires more communication and more meetings, and more time dedicated to synch all that development. If anyone wants old-style ways of working, with more time coding and less meetings I would recommend to go to small companies with limited reach. Their problems are going to be easier managed by a few developers that can focus on creating new things instead of getting up to date with all the complexity that a big corporation requires.
25 years ago internet was as good as everywhere at work and schools in the civilized world and was starting to ramp up in homes. CDs or DVDs were indeed still used for large sets of software and documentation, like stacks of MSDN discs. We even had distibuted source code version control, though it was often only synchronized accross the ocean (e.g. using SERI) overnight.
Personally i like the fact that there are interruptions at work. Working is often a social business and activities like rubber ducking, whiteboarding or live code explanation with living people works wonders for me. It should happen even more.
The people who were coding 8 hours a day, very often were writing yet another framework that they personally came up with to solve a problem, but without duscussing its requirements. More often than not they were making the wrong thing, making too clever things or over engineering.
Fraud is a crime. When a crime is committed citizens inform the police to investigate.
If someone punches you in the street or steals your wallet will you file a lawsuit or call the police? Maybe in America is different, but the normal thing to do is to go to the police. Fraud is not different, the police will investigate.
> If someone punches you in the street or steals your wallet will you file a lawsuit or call the police?
In the USA, probably both. You (or your insurance company) might sue them to recover your financial losses, the police would investigate the crime of assault and/or robbery and pass any evidence along to the prosecutor.
Of course if they have no money or other assets, suing them is a bit pointless.
In the US, you might wait for criminal action if it was progressing to initiate civil action because (1) a criminal conviction can be used as evidence (and it is asymmetrical, because an actual doesn't have the same weight), and (2) criminal process can result in a restitution order which makes civil action unnecessary (and in some jurisdictions may allow recovery from a dedicated fund for victims of crime even if no recovery is possible from the perpetrator, and in that sense may be better than winning a civil action), and (3) criminal prosecution doesn't cost the victim money, civil prosecution generally does.
When anybody wonders why everything is getting worse and more expensive, remember that all the money to create new better products is being redirected to this clusterfuck.
What could we have if all that massive amount of money was used in one other field. (Or many others, there is too much money to invest effectively in just one thing)
So now holding politicians accountable is being an extremist?
If the EU politicians start working against my interests as a citizen, then why shouldn't I penalize them? If the EU as a whole starts working against my interests as a citizen, when why should I keep supporting this system?
The fact that you label me as an extremist for voicing my opinion (which I can only assume is different from yours) is telling. Your view of democracy seems quite skewed and if you were in charge of my country, you can bet I would vote you out too.
This is a forum where everyone is free to participate. If you don't like opinions different from yours, then feel free to skip them instead of insulting other people. This is not high school.
No, that's like pretending the weapons weren't already available. Everyone had assault rifles for two decades, giving access to smart rifles isn't really changing anything about the nature of the problem.
> But if picturing that guy running the show feels like a disaster, then let’s be honest: the issue isn’t the absence of regulation, it’s the desire to force the world into your preferred shape.
For example, we can forbid corporations usage of algorithms beyond sorting by date of the post. Regulation could forbid gathering data about users, no gender, no age, no all the rest of things.
> Calling it “regulation” is just a polite veneer over wanting control.
It is you that may have misinterpreted what regulations are.
> or example, we can forbid corporations usage of algorithms beyond sorting by date of the post
Hacker News sorted by "new" is far less valuable to me than the default homepage which has a sorting algorithm that has a good balance between freshness and impact. Please don't break it.
> It is you that may have misinterpreted what regulations are.
The definition of regulation is literally: "a rule or directive made and maintained by an authority." I am just scared about who the authority is going to be.
So, it seems that it has long lasting effects on everybody. The main difference is how severe are that effects.
> Structural MRI studies have also identified alterations in brain morphology among COVID-RHC, including reductions in grey matter volume, thickness and global brain volume when compared with healthy controls
That is scary.
> Furthermore, long-term follow-up studies are crucial to determine whether the identified brain changes are progressive, stable or dynamic over time.
This is interesting, thou. Is it permanent, it gets worse or better? That makes a big difference and it may also justify further studies and actions.
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